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CCBBI Talk Series Presents: Anastasia Yendiki, Ph.D.

Anastasia Yendiki
December 13, 2019
1:00PM - 2:00PM
Psychology Building, Room 35

Date Range
Add to Calendar 2019-12-13 13:00:00 2019-12-13 14:00:00 CCBBI Talk Series Presents: Anastasia Yendiki, Ph.D. The CCBBI Presents: Anastasia Yendiki, Ph.D. Associate Professor, Harvard Medical School. Associate Investigator, Massachusetts General Hospital, Martinos Center for Biomedical Imaging Talk Title: Mapping the wiring of the brain with diffusion MRI: Current tools and future prospects Abstract: Diffusion MRI is the only imaging modality that allows us to reconstruct the wiring of the human brain in vivo. In recent years, initiatives like the human connectome project have led to the availiability of large collections of diffusion MRI data with unprecedented quality. However, the tractography methods used for analyzing such data are still prone to errors and ambiguities. In this talk, I will first give an overview of the tools that we have developed for reconstructing white-matter pathways from diffusion MRI, for both cross-sectional and longitudinal studies and across the human lifespan. The common theme of these methods is that they define white-matter bundles in a manner that does not require accurate alignment to a brain template, making them robust to individual variability and to the effects of disease or healthy development and aging. Furthermore, these tools can harness the high quality of connectome-style data to improve the analysis of lower-quality,more routinely acquired scans. Finally, I will discuss our work on post mortem validation of diffusion MRI, and the insights that it provides for how we should be acquiring and analyzing our in vivo data.  The CCBBI Talk Series and MRI Users Meetings foster the exchange of experience and expertise in neuroimaging among MRI users at OSU, as well as with external speakers (through the CCBBI Talk Series). The main focus is on methodological aspects of MRI research and experiment design and also serves to highlight novel approaches and topics. The meetings offer a space for lively exchange of the ideas that benefit all users, to make the best possible use of technologies available in the CCBBI. Meetings are generally held on the first Friday of every month at 1:00pm in the Psychology Building, Room 35. To receive meeting detals and related MRI announcements, please complete a request form and specify that you would like to be added to the CCBBI mailing list.   Psychology Building, Room 35 Department of Psychology ASC-psychmainoffice@osu.edu America/New_York public

The CCBBI Presents: Anastasia Yendiki, Ph.D. Associate Professor, Harvard Medical School. Associate Investigator, Massachusetts General Hospital, Martinos Center for Biomedical Imaging

Talk Title: Mapping the wiring of the brain with diffusion MRI: Current tools and future prospects

Abstract: Diffusion MRI is the only imaging modality that allows us to reconstruct the wiring of the human brain in vivo. In recent years, initiatives like the human connectome project have led to the availiability of large collections of diffusion MRI data with unprecedented quality. However, the tractography methods used for analyzing such data are still prone to errors and ambiguities. In this talk, I will first give an overview of the tools that we have developed for reconstructing white-matter pathways from diffusion MRI, for both cross-sectional and longitudinal studies and across the human lifespan. The common theme of these methods is that they define white-matter bundles in a manner that does not require accurate alignment to a brain template, making them robust to individual variability and to the effects of disease or healthy development and aging. Furthermore, these tools can harness the high quality of connectome-style data to improve the analysis of lower-quality,more routinely acquired scans. Finally, I will discuss our work on post mortem validation of diffusion MRI, and the insights that it provides for how we should be acquiring and analyzing our in vivo data. 

The CCBBI Talk Series and MRI Users Meetings foster the exchange of experience and expertise in neuroimaging among MRI users at OSU, as well as with external speakers (through the CCBBI Talk Series). The main focus is on methodological aspects of MRI research and experiment design and also serves to highlight novel approaches and topics. The meetings offer a space for lively exchange of the ideas that benefit all users, to make the best possible use of technologies available in the CCBBI. Meetings are generally held on the first Friday of every month at 1:00pm in the Psychology Building, Room 35. To receive meeting detals and related MRI announcements, please complete a request form and specify that you would like to be added to the CCBBI mailing list.