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Dr. Megha Sehgal

Megha Sehgal

Dr. Megha Sehgal

Assistant Professor, Behavioral Neuroscience


047 Psychology Building
1835 Neil Ave.
Columbus, OH.

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  • PhD: University of Wisconsin-Milwaukee
  • Postdoctoral training: University of California, Los Angeles


Giovanniello, J.R.; Paredes, N.; Wiener, A.; Ramírez-Armenta, K.; Oragwam, C.; Uwadia ,H.O.; Lim, K.; Nnamdi, G.; Wang, A.; Sehgal, M.; Reis, MCV F.; Sias, A.; Silva, A.J.; Adhikari, A.; Malvaez, M.; Wassum.K. A dual-pathway architecture enables chronic stress to promote habit formation. bioRxiv 2023.10.03.560731; doi: https://doi.org/10.1101/2023.10.03.560731

Reis, MCV F., Maesta-Pereira, S., Olivier, M., Schuette, P.J., Sethi, E., Iniguez, E., Chakerian, M., Vaughn, E., Sehgal, M., Nguyen, D.C.T., Yuan, F., Torossian, A., Ikebara, J.M., Kihara, A.H., Dulac, C., Silva, A.J., Kao, J., Khakh, B, Adhikari A (2023). Control of feeding by a bottom-up midbrain-subthalamic pathway. (in revision). 

Sehgal, M., Filho, D.A., Martin, S., Mejia, I.D., Kastellakis, G., Kim, S., Lee, J., Pekcan, A., Huang, S., Lavi, A., Heo, W.D., Poirazi, P., Trachtenberg, J.T., Silva, A.J. (2022). Co-allocation to overlapping dendritic branches in the retrosplenial cortex integrates contextual memories across time. bioRxiv 2021.10.28.466343; doi: https://doi.org/10.1101/2021.10.28.466343 (in revision). 

Sehgal, M., Ehlers, V. E., & Moyer, J. R. (2023). Synaptic and intrinsic plasticity within overlapping lateral amygdala ensembles following fear conditioning. Frontiers in Cellular Neuroscience17, 1221176. https://doi.org/10.3389/fncel.2023.1221176

Guo, C., Blair, G. J., Sehgal, M., Sangiuliano Jimka, F. N., Bellafard, A., Silva, A. J., Golshani, P., Basso, M. A., Blair, H. T., & Aharoni, D. (2023). Miniscope-LFOV: A large-field-of-view, single-cell-resolution, miniature microscope for wired and wire-free imaging of neural dynamics in freely behaving animals. Science Advances. https://www.science.org/doi/10.1126/sciadv.adg3918.

Lavi, A., Sehgal, M., de Sousa, A.F., Ter-Mkrychyan, D., Sisan, F., Luchetti, A, Okabe, Bear, C, A., Silva, A.J. (2022) A retrograde mechanism coordinates memory allocation across brain regions. Neuron. doi: https://doi.org/10.1016/j.neuron.2022.11.018.

Wang, W; Schuette, P.J.; La-Vu, M.Q.; Tobias, B.C.; Čeko, M; Kragel, P.A.; Reis, F.M.C.V.; Ji, S; Sehgal, M; Maesta-Pereira, S; Chakerian, M; Silva, A.J.; Canteras, N. S.; Wager, T.D.; Kao, J.C.; Adhikari, A. (2021) Dorsal premammillary projection to periaqueductal gray controls escape vigor from innate and conditioned threats. ELife. https://elifesciences.org/articles/69178

Yousuf, H., Ehlers, V.E., Sehgal, M., Song, C., & & Moyer, J. R., Jr. (2020) Modulation of intrinsic excitability as a function of learning within the fear conditioning circuit. Neurobiology of learning and memory. doi: https://doi.org/10.1016/j.nlm.2019.107132

Sehgal, M., Zhou, M., Lavi, A., Huang, S., Zhou,Y., & Silva, A.J. (2018). Memory allocation mechanisms underlie memory linking across time. Neurobiology of learning and memorydoi: 10.1016/j.nlm.2018.02.021

Lisman, J., Cooper, K., Sehgal, M. & Silva, A.J. (2018). Memory formation depends on both synapse-specific modifications of synaptic strength and on cellularly-specific increases in excitability. Nature Neurosciencehttps://doi.org/10.1038/s41593-018-0076-6

Sehgal, M., Zhou, M., Cai, D.J., Lavi, A., Huang, S., & Silva, A.J. (2017). 4.32 - Allocating, Tagging, and Linking Memories, In Learning and Memory: A Comprehensive Reference (Second Edition), edited by John H. Byrne, Academic Press, Oxford, 2017, Pages 621-636, ISBN 9780128052914. 

Zhou, M., Greenhill, S., Huang, S.,Silva, T.K., Sano, Y., Wu, S., Cai, Y.,Nagaoka, Y., Sehgal, M.,Cai, D.J., Lee, Y., Fox, K., & Silva, A.J. (2016). CCR5 is a suppressor for cortical plasticity, and hippocampal learning and memory. eLife.  https://doi.org/10.7554/eLife.20985

Sehgal, M., Ehlers, V.E. & Moyer, J. R., Jr. (2014). Learning enhances intrinsic excitability in a subset of lateral amygdala neurons. Learning and Memory. doi: 10.1101/lm.032730.113. 

Sehgal, M., Song, C., Ehlers, V.E. & Moyer, J. R., Jr. (2013). Learning to learn – intrinsic plasticity as a metaplasticity mechanism for memory formation. Neurobiology of learning and memoryhttps://doi.org/10.1016/j.nlm.2013.07.008.

Song, C., Detert, J. A., Sehgal, M., and Moyer, J. R., Jr. (2012). Trace fear conditioning enhances synaptic and intrinsic plasticity in rat hippocampus. Journal of Neurophysiology. doi: 10.1152/jn.00692.2011.