January 18, 2023
3:00PM
-
4:00PM
Psychology Building 035 and via Zoom
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2023-01-18 15:00:00
2023-01-18 16:00:00
Megha Sehgal, PhD., University of California, Los Angeles
Co-allocation to overlapping dendritic branches in the retrosplenial cortex integrates memories across time
Events occurring close in time are often linked in memory, providing a framework for those memories. Recent studies suggest that memories acquired close in time are encoded by overlapping neuronal ensembles, but whether dendritic plasticity plays a role is unknown. Using in vivo longitudinal imaging of somas, dendrites, and spines along with activity-dependent manipulations of these compartments, we show that memory linking is not only dependent on ensemble overlap in
the retrosplenial cortex, but also on branch-specific dendritic allocation mechanisms. These results reveal a novel set of rules that govern how linked, and independent memories are allocated to dendritic compartments.
Psychology Building 035 and via Zoom
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2023-01-18 15:00:00
2023-01-18 16:00:00
Megha Sehgal, PhD., University of California, Los Angeles
Co-allocation to overlapping dendritic branches in the retrosplenial cortex integrates memories across time
Events occurring close in time are often linked in memory, providing a framework for those memories. Recent studies suggest that memories acquired close in time are encoded by overlapping neuronal ensembles, but whether dendritic plasticity plays a role is unknown. Using in vivo longitudinal imaging of somas, dendrites, and spines along with activity-dependent manipulations of these compartments, we show that memory linking is not only dependent on ensemble overlap in
the retrosplenial cortex, but also on branch-specific dendritic allocation mechanisms. These results reveal a novel set of rules that govern how linked, and independent memories are allocated to dendritic compartments.
Psychology Building 035 and via Zoom
America/New_York
public
Co-allocation to overlapping dendritic branches in the retrosplenial cortex integrates memories across time
Events occurring close in time are often linked in memory, providing a framework for those memories. Recent studies suggest that memories acquired close in time are encoded by overlapping neuronal ensembles, but whether dendritic plasticity plays a role is unknown. Using in vivo longitudinal imaging of somas, dendrites, and spines along with activity-dependent manipulations of these compartments, we show that memory linking is not only dependent on ensemble overlap in
the retrosplenial cortex, but also on branch-specific dendritic allocation mechanisms. These results reveal a novel set of rules that govern how linked, and independent memories are allocated to dendritic compartments.
