Dr. Jasmeet Hayes
Associate Professor, Clinical Area
Research in the MINDSET lab is focused on understanding the chronic effects of brain injury and psychological stress on the human brain and health outcomes. We use neuroscience tools such as Magnetic Resonance Imaging (MRI) including structural T1-weighted imaging, diffusion tensor imaging, and fMRI to examine potential links between trauma and neurodegenerative disease. In addition, a primary focus in the lab is to investigate the neural correlates of cognitive processes such as memory and attention, social and emotional processes. We also examine how genetic and epigenetic factors moderate outcomes after injury and through the aging process. Our research investigates the long-term consequences of injury to the brain, including links to neurodegenerative diseases such as Alzheimer's disease, and interactions with mental health disorders.
Dennis, E.,...Hayes, J.P., et al. (accepted). Altered white matter microstructural organization in posttraumatic stress disorder across 3,047 adults: Results from the PGC-ENIGMA PTSD Corsortium. Molecular Psychiatry.
Hayes, J.P. (2019). PTSD and TBI comorbidity. PTSD Research Quarterly, 30, 1-18.
Sullivan, D.R., Marx, B., *Chen, M.S., Depue, B.E., Hayes, S.M., & Hayes, J.P. (2019). Behavioral and neural correlates of memory suppression in PTSD. Journal of Psychiatric Research, 112, 30-37.
Hayes, J.P., Reagan, A., Logue, M.W., Hayes, S.M., Sadeh, N., Miller, D.R., Verfaellie, M., Wolf, E.J., McGlinchey, R.E., Milberg, W.P., Stone, A., Schichman, S.A., & Miller, M.W. (2018). BDNF genotype is associated with hippocampal volume in mild traumatic brain injury. Genes, Brain and Behavior, 17, 107-117.
Hayes, J.P., Logue, M.W., Sadeh, N., Spielberg, J.M., Verfaellie, M., Hayes, S.M., Reagan, A., Salat, D.H., Wolf, E.J., Mcglinchey, R.E., Milberg, W.P., Stone, A., Schichman, S.A. & Miller, M.W. (2017). Mild traumatic brain injury is associated with reduced cortical thickness in those at risk for Alzheimer's disease. Brain, 140, 813-825.
Hayes, J.P., Hayes, S.M., Miller, D.R., Lafleche, G., Logue, M.W. & Verfaellie, M. (2017). Automated measurement of hippocampal subfields in PTSD: Evidence for smaller dentate gyrus volume. Journal of Psychiatric Research, 95, 247-252.
Kim, S., Han, S.C., Gallan, A.J., & Hayes, J.P. (2017). Neurometabolic indicators of mitochondrial dysfunction in repetitive mild traumatic brain injury. Concussion, 2(3), CNC48.
Hayes, J.P., Logue, M.W., Reagan, A., Salat, D., Wolf, E.J., Sadeh, N., Spielberg, J.M., Sperbeck, E., Hayes, S.M., McGlinchey, R.E. & Milberg, W.P., (2017). COMT Val158Met polymorphism moderates the association between PTSD symptom severity and hippocampal volume. Journal of Psychiatry & Neuroscience, 42, 95-102.
Hayes, J.P., Bigler, E.D. & Verfaellie, M. (2016). Traumatic brain injury as a disorder of brain connectivity. Journal of the International Neuropsychological Society, 22, 120-137.
Hayes, J.P., Miller, D.R., Lafleche, G., Salat, D.H. & Verfaellie, M. (2015). The nature of white matter abnormalities in blast-related mild traumatic brain injury. NeuroImage: Clinical, 8, 148-156.